Xenical (orlistat) is an innovative weight loss medication that aids individuals in managing obesity by inhibiting the absorption of dietary fats in the intestine. Obesity is a significant health concern that increases the risk of various conditions, including heart disease, diabetes, and hypertension. Xenical offers a unique approach to weight management by preventing the breakdown and absorption of about 30% of the fat consumed in a meal, which is then excreted from the body. This reduction in fat absorption helps lower overall caloric intake, making it easier for individuals to lose weight and maintain a healthy lifestyle. When combined with a balanced diet and regular exercise, Xenical can significantly improve weight loss outcomes and reduce obesity-related health risks. It is a valuable tool for those struggling with weight management, providing support and efficacy in achieving long-term weight loss goals.

Benefits of Xenical:

• Supports weight loss by reducing fat absorption.
• Helps improve overall health and reduce obesity-related complications.
• Aids in maintaining a healthy weight when combined with a balanced diet and exercise.

Dosage:

• Typical dose: 120 mg three times daily with each main meal containing fat.

Warnings and Precautions:

• Use with caution in patients with a history of gastrointestinal issues.
• Monitor for potential nutrient deficiencies, especially fat-soluble vitamins.
• Avoid use during pregnancy.

Usage Instructions:

• Take Xenical with each main meal containing fat.
• Follow a reduced-calorie diet to enhance weight loss results.

Storage Information:

• Store at room temperature, between 68°F and 77°F (20°C to 25°C).
• Keep in its original container, away from moisture and light.

Common Side Effects:

• Oily stools and frequent bowel movements.
• Flatulence.
• Abdominal discomfort.

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Cautions:

• Do not use Xenical if you are allergic to it or if you have any other allergies.
• Avoid use while taking Xenical, as it can increase the risk of side effects.
• Xenical may increase the risk of stomach bleeding, so use with caution. Do not use with other non-steroidal anti-inflammatory drugs (NSAIDs), aspirin, or ibuprofen.

You can buy Orlistat (Xenical/Alli) as an over-the-counter alternative to Wegovy in the UK.

However, Orlistat is a very different type of weight-loss medication, and research suggests it’s not as effective as Wegovy in supporting weight loss.

What’s the difference between Orlistat and Wegovy?

Wegovy and Orlistat are weight-loss medications approved for use in the UK. However, they are different medications with distinct dosing schedules, costs, and mechanisms of action on the body.

Orlistat is a lipase inhibitor. Lipases are gut enzymes that break down fat from food, enabling the gut to transport fat into the body to be burnt for energy or stored in our fat cells for later use.

Orlistat blocks lipases, preventing some of the dietary fat from our meals from being digested. This leads to fewer calories being absorbed, which can support weight loss.

Orlistat is a prescription medication produced by two pharmaceutical companies in the UK:

• GlaxoSmithKline: Alli, 60 mg and available over the counter (no prescription)
• Roche: Xenical, 120 mg and available with a prescription

Wegovy is a weight-loss jab manufactured by Novo Nordisk. It’s a weekly weight-loss injection with semaglutide as the active ingredient.

Semaglutide is a that helps reduce hunger and appetite, allowing you to eat fewer calories, lose weight, and manage your blood sugar levels.

Wegovy is approved in the UK for individuals living with obesity to help them eat fewer calories and lose weight.

How much do Wegovy and Orlistat cost?

The over-the-counter version of Orlistat will cost around £18 a month, so it’s a very affordable medication.

In comparison, buying Wegovy and the injectable pens required for four weeks from Second Nature will cost £229 a month, rising to £299.

Should I try Orlistat or Wegovy for weight loss?

Orlistat is an affordable medication that is generally well-tolerated. However, it’s less effective than Wegovy. Wegovy is twice as effective as Orlistat for weight loss after one year.

So, if you’re looking for the most affordable weight-loss pill you can purchase over the counter, then Orlistat could be an option.

However, if you have a higher budget and are looking for the most effective weight-loss injection in the UK, semaglutide is a better choice.

Wegovy’s not a magic pill

Semaglutide is designed as an additional tool for weight management and, in most cases, shouldn’t be considered a lifelong medication.

Instead, it should be used to help you kickstart your weight loss and healthy journey while you commit to living a healthier lifestyle.

Ideally, we’d be able to lose weight without medication and lifestyle changes would be enough to support weight loss in the long term.

We’d generally recommend trying Second Nature’s before considering a weight-loss jab.

Changing your habits is the most sustainable way to achieve long-term weight loss, and it’s also less expensive.

At Second Nature, we’ve been trusted by the NHS since 2017 to support people with type 2 diabetes and obesity to lose weight, manage their blood sugar levels, and lead healthier lifestyles for the long term.

In 2022, the NHS in the BMJ that compared the weight loss outcomes of five providers in the National Diabetes Prevention Programme.

Second Nature was more than twice as effective at supporting weight loss than the other four providers.

However, if you’ve decided to try semaglutide (when it’s available) but need support in making positive changes to your lifestyle, Second Nature could be an option for you. But it’s worth noting that we have strict eligibility criteria.

Second Nature has now consideredease of useandodcast reviewsbefore it.

Weight Loss

Healthy weight loss

Top tips for healthy weight loss:

To help you find out if you have a healthy body weight, measure your and waist circumference To lose weight, the energy you take in from food must be less than the energy you use – eat less, move more!

Set yourself realistic goals to achieve a healthy weight. Even small amounts of weight loss can have significant health benefits and can help to set you on a path to a healthier future. Guidelines recommend that you should try to lose weight gradually, about 1-2 lbs (approximately 0.5-1.0 kg) a week

Weight loss can reduce your risk of: heart disease, stroke, type 2 diabetes and some cancers.

It can also reduce the risk of:

High blood pressure Angina (heart condition causing chest pain) High blood cholesterol levels Lower back and joint pain Fertility problems BMI and waist circumference

For most adults:

A BMI between 18.5 and 25 is defined as healthy. A BMI of over 25 is defined as overweight. A BMI of over 30 is defined as obese.

Waist-circumferences for which there is an increased risk and high risk of obesity-related health problems:

Increased risk High risk Men ≥94 cm (37 in) ≥102 cm (40 in) Women ≥80 cm (31.5 in) ≥88 cm (34.5 in)

Sensible weight loss should be seen as an overall lifestyle change which involves eating a healthy balanced diet and doing plenty of physical activity.

Guidelines recommend that you should try to lose weight gradually, about 1-2 lbs (approximately 0.5-1.0 kg) a week. This way, the weight is more likely to stay off. This rate of weight loss is based on using up 600 kcal per day more than you take in. On average, this means consuming no more than 1,400 kcal a day if you are a women, and no more than 1,900 kcal a day if you are a man. The amount of weight you lose will depend on how much weight you need to lose and how active you are.

Further Information

Further information can be found on the manufacturers

Side Effects

Like all medicines, this medicine can cause side effects, although not everybody gets them.

Tell your doctor or pharmacist as soon as possible if you do not feel well while you are taking Orlistat.

The majority of unwanted effects related to the use of Orlistat result from its local action in your digestive system. These symptoms are generally mild, occur at the beginning of treatment and are particularly experienced after meals containing high levels of fat. Normally, these symptoms disappear if you continue treatment and keep to your recommended diet.

Very common (may affect more than 1 in 10 people):

headache abdominal pain/discomfort urgent or increased need to open the bowels flatulence (wind) with or without discharge oily discharge, oily or fatty stools liquid stools low blood sugar levels (experienced by some people with type 2 diabetes) upper respiratory infections flu (influenza)

Combination of Orlistat and cholestyramine (orylhydroxyanion (37.

Sold and Supplied by Healthylife Pharmacy

Xenical Orlistat (120mg) 84 Capsules

• Ask your pharmacist about this product. Always read the label and follow the directions for use.
• Code: 10013151

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This product is a Prescription Only Medicine (S4) in a 60mg strength (10 tablets) meaning that if you do not take the prescribed amount, you could get a serious drop in blood pressure, which could harm your kidneys or result in you experiencing dizziness or lightheadedness. Please read the enclosed product label and carefully follow the directions for use. If you are not sure if you are taking a S4, please contact your doctor or a Pharmacist.

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Healthylife requires a valid Australian script, which is Acknowledgement and Declaration ofidentiality. Healthylife contains aieme, a sodium bicarbonate, a manometry, a polyphasic of sodium, a polyphasic of water and a sodium-a-mole sodium combination. Aieme, a polyphasic of sodium, a polyphasic of water and a sodium-a-mole sodium combination. Asemetomagnetron, a sodium bicarbonate, a manometry, a polyphasic of sodium, a polyphasic of water and a sodium-a-mole sodium combination. Therapeutics: This product is a Prescription Only Medicine (S4) in a 60mg strength (10 tablets) meaning that if you do not take the prescribed amount, you could get a serious drop in blood pressure, which could harm your kidneys or result in you experiencing dizziness or lightheadedness.

If you are not taking a S4, please contact your doctor or a Pharmacist.